Positron emission tomography for the evaluation of pancreatic disease.

Journal Article (Journal Article)

Efficient techniques for native-labeling of amino acids have been combined successfully with emission tomography to yield significant improvements in pancreatic imaging. Carbon-11-labeled tryptophan appears to be the best agent available currently for imaging the pancreas. Optimum scanning times begin 30 min after tracer administration. Positron emission tomography with 11C-tryptophan is capable of defining both morphological and functional alterations in the pancreas. Tumors as small as 2 cm in diameter can be detected, but reliable differentiation of pancreatic cancer from pancreatis may not be possible even with this improved imaging technique. Longitudinal multiplane emission tomography in single-photon mode with the Pho/Con provides an efficient and satisfactory approach to pancreatic imaging with the positron-emitting radiopharmaceuticals.

Full Text

Duke Authors

Cited Authors

  • Kirchner, PT; Ryan, J; Zalutsky, M; Harper, PV

Published Date

  • October 1, 1980

Published In

Volume / Issue

  • 10 / 4

Start / End Page

  • 374 - 391

PubMed ID

  • 6968453

International Standard Serial Number (ISSN)

  • 0001-2998

Digital Object Identifier (DOI)

  • 10.1016/s0001-2998(80)80039-0


  • eng

Conference Location

  • United States