Stress, coping, and circadian disruption among women awaiting breast cancer surgery.
Journal Article (Journal Article)
BACKGROUND: Psychological distress and coping related to a breast cancer diagnosis can profoundly affect psychological adjustment, possibly resulting in the disruption of circadian rest/activity and cortisol rhythms, which are prognostic for early mortality in metastatic colorectal and breast cancers, respectively. PURPOSE: This study aims to explore the relationships of cancer-specific distress and avoidant coping with rest/activity and cortisol rhythm disruption in the period between diagnosis and breast cancer surgery. METHODS: Fifty-seven presurgical breast cancer patients provided daily self-reports of cancer-specific distress and avoidant coping as well as actigraphic and salivary cortisol data. RESULTS: Distress and avoidant coping were related to rest/activity rhythm disruption (daytime sedentariness, inconsistent rhythms). Patients with disrupted rest/activity cycles had flattened diurnal cortisol rhythms. CONCLUSIONS: Maladaptive psychological responses to breast cancer diagnosis were associated with disruption of circadian rest/activity rhythms. Given that circadian cycles regulate tumor growth, we need greater understanding of possible psychosocial effects in cancer-related circadian disruption.
- Dedert, E; Lush, E; Chagpar, A; Dhabhar, FS; Segerstrom, SC; Spiegel, D; Dayyat, E; Daup, M; McMasters, K; Sephton, SE
- August 2012
Volume / Issue
- 44 / 1
Start / End Page
- 10 - 20
Electronic International Standard Serial Number (EISSN)
Digital Object Identifier (DOI)