Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy.
Publication
, Journal Article
Gaillard, S; Dinoso, JB; Marsh, JA; DeZern, AE; O'Connell, KA; Spivak, AM; Alwood, K; Durand, CM; Ambinder, RF; Blankson, JN
Published in: J Clin Virol
July 2011
The mechanism of elite control of HIV-1 replication is not fully understood. While immunosuppression due to rituximab based chemotherapy has been associated with increased replication of HBV, CMV, and HIV-1, control of replication-competent HIV-1 was maintained in an elite controller/suppressor treated with a regimen that included vincristine, cyclophosphamide, prednisone, four rounds of plasmapheresis and ten cycles of rituximab. The data suggests that de-novo antibody responses do not play a significant role in the control of viral replication in these patients.
Duke Scholars
Published In
J Clin Virol
DOI
EISSN
1873-5967
Publication Date
July 2011
Volume
51
Issue
3
Start / End Page
195 / 198
Location
Netherlands
Related Subject Headings
- Virology
- Sequence Analysis, DNA
- Rituximab
- Neoplasms
- Molecular Sequence Data
- Middle Aged
- Male
- Immunosuppressive Agents
- Humans
- HIV-1
Citation
APA
Chicago
ICMJE
MLA
NLM
Gaillard, S., Dinoso, J. B., Marsh, J. A., DeZern, A. E., O’Connell, K. A., Spivak, A. M., … Blankson, J. N. (2011). Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. J Clin Virol, 51(3), 195–198. https://doi.org/10.1016/j.jcv.2011.04.002
Gaillard, Stephanie, Jason B. Dinoso, Julia A. Marsh, Amy E. DeZern, Karen A. O’Connell, Adam M. Spivak, Karla Alwood, Christine M. Durand, Richard F. Ambinder, and Joel N. Blankson. “Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy.” J Clin Virol 51, no. 3 (July 2011): 195–98. https://doi.org/10.1016/j.jcv.2011.04.002.
Gaillard S, Dinoso JB, Marsh JA, DeZern AE, O’Connell KA, Spivak AM, et al. Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. J Clin Virol. 2011 Jul;51(3):195–8.
Gaillard, Stephanie, et al. “Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy.” J Clin Virol, vol. 51, no. 3, July 2011, pp. 195–98. Pubmed, doi:10.1016/j.jcv.2011.04.002.
Gaillard S, Dinoso JB, Marsh JA, DeZern AE, O’Connell KA, Spivak AM, Alwood K, Durand CM, Ambinder RF, Blankson JN. Sustained elite suppression of replication competent HIV-1 in a patient treated with rituximab based chemotherapy. J Clin Virol. 2011 Jul;51(3):195–198.
Published In
J Clin Virol
DOI
EISSN
1873-5967
Publication Date
July 2011
Volume
51
Issue
3
Start / End Page
195 / 198
Location
Netherlands
Related Subject Headings
- Virology
- Sequence Analysis, DNA
- Rituximab
- Neoplasms
- Molecular Sequence Data
- Middle Aged
- Male
- Immunosuppressive Agents
- Humans
- HIV-1