Analysis of ectopic pregnancies resulting from in-vitro fertilization and embryo transfer.

Journal Article (Journal Article)

The purpose of this study was to analyse the risk factors, stimulation characteristics, site and outcome of pregnancy and future fecundity of patients who develop ectopic pregnancies after in-vitro fertilization (IVF). Of 3145 transfer cycles between January 1981 and July 1989, 27 (3.3%) of the resulting 825 pregnancies were ectopic. There was a significantly greater incidence of a prior ectopic pregnancy in the study group compared to the controls. Compared to matched controls with intrauterine pregnancies, the study group had significantly higher peak oestradiol levels. Twenty-one ectopic pregnancies were ampullary, two were interstitial, one was abdominal, one was cervical and two were heterotopic. Sixteen of the patients subsequently underwent 40 IVF attempts with a pregnancy rate of 28% per transfer. We conclude that patients with a prior ectopic pregnancy are at risk for an IVF ectopic pregnancy. The subsequent IVF outcome of those who develop ectopic pregnancies after IVF is encouraging.

Full Text

Duke Authors

Cited Authors

  • Karande, VC; Flood, JT; Heard, N; Veeck, L; Muasher, SJ

Published Date

  • March 1, 1991

Published In

Volume / Issue

  • 6 / 3

Start / End Page

  • 446 - 449

PubMed ID

  • 1955556

International Standard Serial Number (ISSN)

  • 0268-1161

Digital Object Identifier (DOI)

  • 10.1093/oxfordjournals.humrep.a137356


  • eng

Conference Location

  • England