Gonadotropin stimulation for in vitro fertilization and embryo transfer in insulin-dependent diabetics: follicular response, oocyte quality, embryo development, and follicular environment.

Journal Article (Journal Article)

Two IDD patients were stimulated with gonadotropins for IVF and ET. Both patients had high E2 response and greater than or equal to 5 preovulatory oocytes retrieved, normal fertilization and cleavage rates, and transfer; neither conceived. Follicular fluid showed levels of E2, P, A, hCG, and PRL similar to non-IDD. Epidermal growth factor could not be detected in FF. Insulin-dependent diabetes patients can undergo gonadotropin stimulation for IVF with customary responses. Their follicular milieu resembles that of non-IDD patients except for a lack of EGF.

Full Text

Duke Authors

Cited Authors

  • Oehninger, S; Hofmann, GE; Kreiner, D; Acosta, AA; Muasher, SJ

Published Date

  • April 1990

Published In

Volume / Issue

  • 53 / 4

Start / End Page

  • 741 - 743

PubMed ID

  • 2108062

International Standard Serial Number (ISSN)

  • 0015-0282

Digital Object Identifier (DOI)

  • 10.1016/s0015-0282(16)53476-1


  • eng

Conference Location

  • United States