A prospective randomized comparison of single- and double-lumen needles for transvaginal follicular aspiration.

Journal Article (Clinical Trial;Journal Article)

Patients undergoing ultrasound-directed transvaginal follicular aspiration in a large in vitro fertilization (IVF) program were randomized for retrieval with either a single-lumen needle (SLN; N = 22) or a double-lumen needle (DLN; N = 22) to compare recovery rates and the technical aspects of their use. Two hundred ten and two hundred two follicles were aspirated with each needle, respectively. Follicular diameters were measured ultrasonically at the time of aspiration and recorded. One or more washes were performed when using the DLN and the SLN was withdrawn each time to recover the fluid in the dead space of the needle. The distribution of follicular sizes was the same for both needles. Oocyte recovery rates (SLN = 65.7%; DLN = 63.9%) and the incidence of fractured zonae (SLN = 9.1%; DLN = 6.4%) were the same for both needles (alpha greater than 0.50; beta less than 0.01). Although there were no differences between the two needles in the number of oocytes provided for IVF, there were technical differences. The DLN needle was more flexible and frequently deviated from the projected path as observed by ultrasound. The SLN may be preferable because it is technically easier to use; however, there may remain specific indications for the use of the DLN.

Full Text

Duke Authors

Cited Authors

  • Scott, RT; Hofmann, GE; Muasher, SJ; Acosta, AA; Kreiner, DK; Rosenwaks, Z

Published Date

  • April 1989

Published In

Volume / Issue

  • 6 / 2

Start / End Page

  • 98 - 100

PubMed ID

  • 2723511

International Standard Serial Number (ISSN)

  • 0740-7769

Digital Object Identifier (DOI)

  • 10.1007/BF01130734


  • eng

Conference Location

  • United States