ODF RECONSTRUCTION IN Q-BALL IMAGING WITH SOLID ANGLE CONSIDERATION.

Published

Journal Article

Q-ball imaging (QBI) is a high angular resolution diffusion imaging (HARDI) technique which has been proven very successful in resolving multiple intravoxel fiber orientations in MR images. The standard computation of the orientation distribution function (ODF, the probability of diffusion in a given direction) from q-ball uses linear radial projection, neglecting the change in the volume element along the ray, thereby resulting in distributions different from the true ODFs. For instance, they are not normalized or as sharp as expected, and generally require post-processing, such as sharpening or spherical deconvolution. In this paper, we consider the mathematically correct definition of the ODF and derive a closed-form expression for it in QBI. The derived ODF is dimensionless and normalized, and can be efficiently computed from q-ball acquisition protocols. We describe our proposed method and demonstrate its significantly improved performance on artificial data and real HARDI volumes.

Full Text

Duke Authors

Cited Authors

  • Aganj, I; Lenglet, C; Sapiro, G

Published Date

  • June 2009

Published In

Volume / Issue

  • 2009 /

Start / End Page

  • 1398 - 1401

PubMed ID

  • 25789084

Pubmed Central ID

  • 25789084

Electronic International Standard Serial Number (EISSN)

  • 1945-8452

International Standard Serial Number (ISSN)

  • 1945-7928

Digital Object Identifier (DOI)

  • 10.1109/isbi.2009.5193327

Language

  • eng