In Situ Formation of Polymer Matrices for Localized Drug Delivery


Journal Article

Polymer matrices can be formed within the body in direct contact with cells and tissues by a variety of techniques, both physicochemical and covalent in nature, including thermal gelation, pH-sensitive gelation, the use of thixotropic materials, precipitation from certain organic solutions photopolymerization, and chemical cross-linking. these types of materials can be injected as liquids and converted to a gel or solid in situ. Many of these polymer systems are appropriate for delivery of peptides and proteins.

Full Text

Duke Authors

Cited Authors

  • West, JL

Published Date

  • January 1, 1997

Published In

Volume / Issue

  • 675 /

Start / End Page

  • 119 - 123

International Standard Serial Number (ISSN)

  • 0097-6156

Digital Object Identifier (DOI)

  • 10.1021/bk-1997-0675.ch007

Citation Source

  • Scopus