Growth signaling at the nexus of stem cell life and death.

Journal Article (Journal Article)

Stress can activate tumor-suppressive mechanisms, causing the loss of adult stem cell function with age. In this issue of Cell Stem Cell and in Nature, Castilho et al. (2009) and Harrison et al. (2009) highlight the importance of mTOR signaling in stem cell exhaustion and mammalian aging, respectively.

Full Text

Duke Authors

Cited Authors

  • Wood, KC; Sabatini, DM

Published Date

  • September 4, 2009

Published In

Volume / Issue

  • 5 / 3

Start / End Page

  • 232 - 234

PubMed ID

  • 19733530

Pubmed Central ID

  • PMC3390250

Electronic International Standard Serial Number (EISSN)

  • 1875-9777

Digital Object Identifier (DOI)

  • 10.1016/j.stem.2009.08.008


  • eng

Conference Location

  • United States