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Retinal thickness on Stratus optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy.

Publication ,  Journal Article
Bressler, NM; Edwards, AR; Antoszyk, AN; Beck, RW; Browning, DJ; Ciardella, AP; Danis, RP; Elman, MJ; Friedman, SM; Glassman, AR; Gross, JG ...
Published in: Am J Ophthalmol
May 2008

PURPOSE: To evaluate optical coherence tomography (OCT) thickness of the macula in people with diabetes but minimal or no retinopathy and to compare these findings with published normative data in the literature from subjects reported to have no retinal disease. DESIGN: Cross-sectional study. METHODS: In a multicenter community- and university-based practices setting, 97 subjects with diabetes with no or minimal diabetic retinopathy and no central retinal thickening on clinical examination and a center point thickness of 225 microm or less on OCT (Stratus OCT; Carl Zeiss Meditec, Dublin, California, USA) were recruited. Electronic Early Treatment of Diabetic Retinopathy Study best-corrected visual acuity, seven-field stereoscopic color fundus photographs, and Stratus OCT fast macular scan were noted. Main outcome measures were central subfield (CSF) thickness measured on Stratus OCT. RESULTS: On average, CSF thickness was 201 +/- 22 microm. CSF thickness was significantly greater in retinas from men than retinas from women (mean +/- standard deviation, 209 +/- 18 microm vs 194 +/- 23 microm; P < .001). After adjusting for gender, no additional factors were found to be associated significantly with CSF thickness (P > .10). CONCLUSIONS: CSF thicknesses on Stratus OCT in people with diabetes and minimal or no retinopathy are similar to thicknesses reported from a normative database of people without diabetes. CSF thickness is greater in men than in women, consistent with many, but not all, previous reports. Studies involving comparisons of retinal thickness with expected norms should consider different mean values for women and men.

Duke Scholars

Published In

Am J Ophthalmol

DOI

ISSN

0002-9394

Publication Date

May 2008

Volume

145

Issue

5

Start / End Page

894 / 901

Location

United States

Related Subject Headings

  • Visual Acuity
  • Tomography, Optical Coherence
  • Retina
  • Reference Values
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Diabetic Retinopathy
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Bressler, N. M., Edwards, A. R., Antoszyk, A. N., Beck, R. W., Browning, D. J., Ciardella, A. P., … Diabetic Retinopathy Clinical Research Network, . (2008). Retinal thickness on Stratus optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy. Am J Ophthalmol, 145(5), 894–901. https://doi.org/10.1016/j.ajo.2007.12.025
Bressler, Neil M., Allison R. Edwards, Andrew N. Antoszyk, Roy W. Beck, David J. Browning, Antonio P. Ciardella, Ronald P. Danis, et al. “Retinal thickness on Stratus optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy.Am J Ophthalmol 145, no. 5 (May 2008): 894–901. https://doi.org/10.1016/j.ajo.2007.12.025.
Bressler NM, Edwards AR, Antoszyk AN, Beck RW, Browning DJ, Ciardella AP, et al. Retinal thickness on Stratus optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy. Am J Ophthalmol. 2008 May;145(5):894–901.
Bressler, Neil M., et al. “Retinal thickness on Stratus optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy.Am J Ophthalmol, vol. 145, no. 5, May 2008, pp. 894–901. Pubmed, doi:10.1016/j.ajo.2007.12.025.
Bressler NM, Edwards AR, Antoszyk AN, Beck RW, Browning DJ, Ciardella AP, Danis RP, Elman MJ, Friedman SM, Glassman AR, Gross JG, Li HK, Murtha TJ, Stone TW, Sun JK, Diabetic Retinopathy Clinical Research Network. Retinal thickness on Stratus optical coherence tomography in people with diabetes and minimal or no diabetic retinopathy. Am J Ophthalmol. 2008 May;145(5):894–901.
Journal cover image

Published In

Am J Ophthalmol

DOI

ISSN

0002-9394

Publication Date

May 2008

Volume

145

Issue

5

Start / End Page

894 / 901

Location

United States

Related Subject Headings

  • Visual Acuity
  • Tomography, Optical Coherence
  • Retina
  • Reference Values
  • Ophthalmology & Optometry
  • Middle Aged
  • Male
  • Humans
  • Female
  • Diabetic Retinopathy