Fast feedback regulation of ACTH by cortisol.
Journal Article
1. Fast feedback regulation of ACTH by cortisol has not been well studied in humans. The authors studied the existence and characteristics of fast feedback regulation in normal humans. 2. Hydrocortisone hemisuccinate was infused at two different rates: 6 mg/hour and 12 mg/hour for two hours. 3. The studies did not demonstrate the existence of fast feedback regulation of basal ACTH concentration by cortisol in man. Further, the response was variable and the rate sensitive character was difficult to demonstrate.
Full Text
Duke Authors
Cited Authors
- Krishnan, KR; Ritchie, JC; Manepalli, AN; Saunders, W; Li, SW; Venkataraman, S; Nemeroff, CB; Carroll, BJ
Published Date
- 1991
Published In
Volume / Issue
- 15 / 4
Start / End Page
- 523 - 529
PubMed ID
- 1661015
Pubmed Central ID
- 1661015
International Standard Serial Number (ISSN)
- 0278-5846
Digital Object Identifier (DOI)
- 10.1016/0278-5846(91)90027-x
Language
- eng
Conference Location
- England