Growth hormone response to growth hormone releasing factor in Alzheimer's disease.
Publication
, Journal Article
Nemeroff, CB; Krishnan, KR; Belkin, BM; Ritchie, JC; Clark, C; Vale, WW; Rivier, JE; Thorner, MO
Published in: Neuroendocrinology
December 1989
Because of the well-established reduction in the concentration of somatostatin in several brain areas of patients with histologically verified Alzheimer's disease, we sought to determine if growth hormone (GH) secretion is altered in Alzheimer's disease. In order to study this, we assessed the GH response to growth hormone releasing factor (GRF) in 8 patients with Alzheimer's disease and 8 age-matched controls. Although there was no difference between the magnitude of the GRF-induced GH response (delta max GH response or area under the curve) between the Alzheimer's disease patients and the controls, the Alzheimer's patients exhibited a delayed GH response to GRF.
Duke Scholars
Published In
Neuroendocrinology
DOI
ISSN
0028-3835
Publication Date
December 1989
Volume
50
Issue
6
Start / End Page
663 / 666
Location
Switzerland
Related Subject Headings
- Middle Aged
- Male
- Humans
- Growth Hormone-Releasing Hormone
- Growth Hormone
- Female
- Endocrinology & Metabolism
- Alzheimer Disease
- Aged, 80 and over
- Aged
Citation
APA
Chicago
ICMJE
MLA
NLM
Nemeroff, C. B., Krishnan, K. R., Belkin, B. M., Ritchie, J. C., Clark, C., Vale, W. W., … Thorner, M. O. (1989). Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology, 50(6), 663–666. https://doi.org/10.1159/000125296
Nemeroff, C. B., K. R. Krishnan, B. M. Belkin, J. C. Ritchie, C. Clark, W. W. Vale, J. E. Rivier, and M. O. Thorner. “Growth hormone response to growth hormone releasing factor in Alzheimer's disease.” Neuroendocrinology 50, no. 6 (December 1989): 663–66. https://doi.org/10.1159/000125296.
Nemeroff CB, Krishnan KR, Belkin BM, Ritchie JC, Clark C, Vale WW, et al. Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology. 1989 Dec;50(6):663–6.
Nemeroff, C. B., et al. “Growth hormone response to growth hormone releasing factor in Alzheimer's disease.” Neuroendocrinology, vol. 50, no. 6, Dec. 1989, pp. 663–66. Pubmed, doi:10.1159/000125296.
Nemeroff CB, Krishnan KR, Belkin BM, Ritchie JC, Clark C, Vale WW, Rivier JE, Thorner MO. Growth hormone response to growth hormone releasing factor in Alzheimer's disease. Neuroendocrinology. 1989 Dec;50(6):663–666.
Published In
Neuroendocrinology
DOI
ISSN
0028-3835
Publication Date
December 1989
Volume
50
Issue
6
Start / End Page
663 / 666
Location
Switzerland
Related Subject Headings
- Middle Aged
- Male
- Humans
- Growth Hormone-Releasing Hormone
- Growth Hormone
- Female
- Endocrinology & Metabolism
- Alzheimer Disease
- Aged, 80 and over
- Aged