Xenon/CT blood flow mapping of the kidney and liver.


Journal Article

A noninvasive technique for measuring blood flow by xenon-enhanced X-ray transmission CT has been developed and reported quite extensively in recent years. In this method nonradioactive xenon gas is inhaled, and the temporal changes in radiographic enhancement produced by the inhalation are measured by sequential CT. Time-dependent xenon concentration within various tissue segments is used to derive local blood flow maps. The method has been amply discussed in relation to assessment of local cerebral blood flow. Its application to other body organs is explored in this paper, in which results from six preliminary blood flow studies in the liver and kidneys of nonhuman primates are reported. Blood flow in renal cortex ranged from 150 to 280 ml/100 cc/min and hepatic tissue perfusion from 80 to 120 ml/100 cc/min. The advantages and limitations of the method in such applications are discussed.

Full Text

Cited Authors

  • Gur, D; Yonas, H; Wolfson, SK; Wozney, P; Colsher, JG; Good, WF; Good, BC; Herbert, DL; Cook, EE

Published Date

  • December 1984

Published In

Volume / Issue

  • 8 / 6

Start / End Page

  • 1124 - 1127

PubMed ID

  • 6501620

Pubmed Central ID

  • 6501620

International Standard Serial Number (ISSN)

  • 0363-8715

Digital Object Identifier (DOI)

  • 10.1097/00004728-198412000-00015


  • eng

Conference Location

  • United States