Nucleolar dominance in polytene cells of Drosophila.

Journal Article (Journal Article)

Previous studies indicate that genes from only one of the cell's nucleolus organizers undergo multiple rounds of DNA replication in polytene cells of Drosophila. This report presents evidence that this effect is mediated by a function that is associated with the ribosomal genes of the dominant or replicating X chromosome. This function can act in trans to result in replication of the ribosomal genes on the recessive X chromosome in flies that are bobbed for the dominant X chromosome. In these cases, ribosomal genes from both chromosomes undergo polytenization. Heterochromatic regions that flank the nucleolus organizer have little or no effect on nucleolar dominance. In addition, deletion of the compensatory response (cr(+)) locus does not affect the dominance, suggesting that ribosomal gene compensation and nucleolar dominance in polytene cells of Drosophila are separate genetic phenomena.

Full Text

Duke Authors

Cited Authors

  • Endow, SA

Published Date

  • July 1983

Published In

Volume / Issue

  • 80 / 14

Start / End Page

  • 4427 - 4431

PubMed ID

  • 16593337

Pubmed Central ID

  • PMC384051

International Standard Serial Number (ISSN)

  • 0027-8424

Digital Object Identifier (DOI)

  • 10.1073/pnas.80.14.4427


  • eng

Conference Location

  • United States