Pilot Study of Caffeine Abstinence for Control of Chronic Glucose in Type 2 Diabetes.

Journal Article (Journal Article)

BACKGROUND: A growing body of evidence suggests that caffeinated beverages may impair chronic glucose control in type 2 diabetes. This pilot study tested the chronic effects of caffeine abstinence on glucose control in type 2 diabetic patients who were daily coffee drinkers. METHODS: Twelve coffee drinkers (six males) with established type 2 diabetes participated. Seven (five males) completed 3 months of total caffeine abstinence. Measures of chronic glucose control, long-term (hemoglobin A1c [HbA1c]) and short-term (1,5-anhydroglucitol [1,5-AG]), were collected at baseline and during follow-up. Abstinence was established by diaries confirmed by saliva caffeine assays. RESULTS: Abstinence produced significant decreases in HbA1c and increases in 1,5-AG, both indicating improvements in chronic glucose control. Fasting glucose and insulin did not change, nor were changes in body weight observed. CONCLUSIONS: Although preliminary, these results suggest that caffeine abstinence may be beneficial for patients with type 2 diabetes. This hypothesis should be confirmed in larger controlled clinical trials.

Full Text

Duke Authors

Cited Authors

  • Lane, JD; Lane, AJ; Surwit, RS; Kuhn, CM; Feinglos, MN

Published Date

  • May 24, 2012

Published In

Volume / Issue

  • 2 / 1

Start / End Page

  • 45 - 47

PubMed ID

  • 23209999

Pubmed Central ID

  • PMC3510748

International Standard Serial Number (ISSN)

  • 2156-5783

Digital Object Identifier (DOI)

  • 10.1089/jcr.2012.0003


  • eng

Conference Location

  • United States