The influence of prior obstetrical history on current 17-hydroxyprogesterone caproate use.


Journal Article

OBJECTIVE: To determine if gestational age of prior preterm delivery influences a woman's receipt of 17-hydroxyprogesterone caproate (17-OHP-C). METHODS: Retrospective cohort of women eligible for 17-OHP-C at Duke Obstetrics Clinic were identified by medical record review. Sociodemographic and clinical characteristics were abstracted. Results. Of 104 eligible subjects, 82 (78.8%) were offered 17-OHP-C. Of these, thirty-four (41.5%) declined. The median gestational age of the most recent preterm delivery was significantly lower among subjects who accepted 17-OHP-C as compared to those who declined (28.7 vs. 34.0 weeks, P = .02) and in subjects offered 17-OHP-C compared to those not offered 17-OHP-C (30.2 vs. 36.0 weeks, P = .03). Subjects not offered 17-OHP-C were more likely to have had an interval term delivery (31.8% vs. 9.7%, P = .009) CONCLUSION: Women with earlier preterm deliveries were more likely to be offered and accept 17-OHP-C. Prior obstetric history may influence both providers' and patients' willingness to discuss and/or accept 17-OHP-C.

Full Text

Cited Authors

  • Ransom, CE; Chin, JR; Roeder, HA; Sinclair, TR; Heine, RP; Murtha, AP

Published Date

  • January 2011

Published In

Volume / Issue

  • 2011 /

Start / End Page

  • 286483 -

PubMed ID

  • 21773029

Pubmed Central ID

  • 21773029

Electronic International Standard Serial Number (EISSN)

  • 2090-2735

International Standard Serial Number (ISSN)

  • 2090-2727

Digital Object Identifier (DOI)

  • 10.1155/2011/286483


  • eng