Treatment for Uterine Fibroids: Searching for Effective Drug Therapies.


Journal Article

Uterine fibroids are common reproductive-age benign tumors that contribute to severe morbidity and infertility. Cumulative incidence is 4 times higher in Africian-Americans compared to Caucasians and constitutes a major health disparity challenge. Fibroids are the leading indication for hysterectomy and their management averages $21 billion annually in the US. No long term minimally invasive therapies exist. Thus, promising drug therapies, their chemistry, pharmacology, and clinical efficacy, focusing first on innovative drug delivery approaches, are reviewed.

Full Text

Duke Authors

Cited Authors

  • Taylor, DK; Leppert, PC

Published Date

  • 2012

Published In

Volume / Issue

  • 9 / 1

Start / End Page

  • e41 - e49

PubMed ID

  • 23264802

Pubmed Central ID

  • 23264802

International Standard Serial Number (ISSN)

  • 1740-6773

Digital Object Identifier (DOI)

  • 10.1016/j.ddstr.2012.06.001


  • eng

Conference Location

  • Netherlands