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CASS in retrospect: lessons from the randomized cohort and registry. Coronary Artery Surgery Study.

Publication ,  Journal Article
Holloway, JD; Schocken, DD
Published in: Am J Med Sci
May 1988

The Coronary Artery Surgery Study (CASS) was a prospective, randomized evaluation of the value of coronary artery bypass grafting compared with medical therapy for stable, mildly symptomatic coronary artery disease. Also, the CASS registry collected clinic information and follow-up data from 24,959 nonconsecutive patients undergoing cardiac catheterization from 1974 to 1979. CASS has had a major impact on current management of the coronary disease patient and represents an important contribution to the cardiovascular knowledge base. Despite the large size and valuable contributions of CASS, its findings have been widely misinterpreted, especially regarding indications for coronary artery bypass surgery. This review examines CASS from the viewpoint of its methodology and some of its many published reports. A full understanding of CASS is requisite to avoid clinical misapplication of the findings of this study.

Duke Scholars

Published In

Am J Med Sci

DOI

ISSN

0002-9629

Publication Date

May 1988

Volume

295

Issue

5

Start / End Page

424 / 432

Location

United States

Related Subject Headings

  • United States
  • Registries
  • Random Allocation
  • Prospective Studies
  • National Institutes of Health (U.S.)
  • Male
  • Humans
  • General & Internal Medicine
  • Female
  • Evaluation Studies as Topic
 

Citation

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Chicago
ICMJE
MLA
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Holloway, J. D., & Schocken, D. D. (1988). CASS in retrospect: lessons from the randomized cohort and registry. Coronary Artery Surgery Study. Am J Med Sci, 295(5), 424–432. https://doi.org/10.1097/00000441-198805000-00003
Holloway, J. D., and D. D. Schocken. “CASS in retrospect: lessons from the randomized cohort and registry. Coronary Artery Surgery Study.Am J Med Sci 295, no. 5 (May 1988): 424–32. https://doi.org/10.1097/00000441-198805000-00003.
Holloway JD, Schocken DD. CASS in retrospect: lessons from the randomized cohort and registry. Coronary Artery Surgery Study. Am J Med Sci. 1988 May;295(5):424–32.
Holloway, J. D., and D. D. Schocken. “CASS in retrospect: lessons from the randomized cohort and registry. Coronary Artery Surgery Study.Am J Med Sci, vol. 295, no. 5, May 1988, pp. 424–32. Pubmed, doi:10.1097/00000441-198805000-00003.
Holloway JD, Schocken DD. CASS in retrospect: lessons from the randomized cohort and registry. Coronary Artery Surgery Study. Am J Med Sci. 1988 May;295(5):424–432.
Journal cover image

Published In

Am J Med Sci

DOI

ISSN

0002-9629

Publication Date

May 1988

Volume

295

Issue

5

Start / End Page

424 / 432

Location

United States

Related Subject Headings

  • United States
  • Registries
  • Random Allocation
  • Prospective Studies
  • National Institutes of Health (U.S.)
  • Male
  • Humans
  • General & Internal Medicine
  • Female
  • Evaluation Studies as Topic