NLRP3 Inflammasome and MS/EAE.
Publication
, Journal Article
Inoue, M; Shinohara, ML
Published in: Autoimmune Dis
2013
Inflammasomes are cytosolic sensors that detect pathogens and danger signals in the innate immune system. The NLRP3 inflammasome is currently the most fully characterized inflammasome and is known to detect a wide array of microbes and endogenous damage-associated molecules. Possible involvement of the NLRP3 inflammasome (or inflammasomes) in the development of multiple sclerosis (MS) was suggested in a number of studies. Recent studies showed that the NLRP3 inflammasome exacerbates experimental autoimmune encephalomyelitis (EAE), an animal model of MS, although EAE can also develop without the NLRP3 inflammasome. In this paper, we discuss the NLRP3 inflammasome in MS and EAE development.
Duke Scholars
Altmetric Attention Stats
Dimensions Citation Stats
Published In
Autoimmune Dis
DOI
ISSN
2090-0422
Publication Date
2013
Volume
2013
Start / End Page
859145
Location
United States
Citation
APA
Chicago
ICMJE
MLA
NLM
Inoue, M., & Shinohara, M. L. (2013). NLRP3 Inflammasome and MS/EAE. Autoimmune Dis, 2013, 859145. https://doi.org/10.1155/2013/859145
Inoue, Makoto, and Mari L. Shinohara. “NLRP3 Inflammasome and MS/EAE.” Autoimmune Dis 2013 (2013): 859145. https://doi.org/10.1155/2013/859145.
Inoue M, Shinohara ML. NLRP3 Inflammasome and MS/EAE. Autoimmune Dis. 2013;2013:859145.
Inoue, Makoto, and Mari L. Shinohara. “NLRP3 Inflammasome and MS/EAE.” Autoimmune Dis, vol. 2013, 2013, p. 859145. Pubmed, doi:10.1155/2013/859145.
Inoue M, Shinohara ML. NLRP3 Inflammasome and MS/EAE. Autoimmune Dis. 2013;2013:859145.
Published In
Autoimmune Dis
DOI
ISSN
2090-0422
Publication Date
2013
Volume
2013
Start / End Page
859145
Location
United States