Nascent nitrosylases.


Journal Article

Protein S-nitrosylation is thought to be mediated primarily by nitric oxide synthases. S-nitrosylated GAPDH is now shown to function within signal transduction cascades as a nuclear nitrosylase. Along with other recent demonstrations of regulated protein-protein transnitrosylation, these findings point to a new mechanism of signal transduction with transformative implications for nitric oxide biology and redox signalling.

Full Text

Duke Authors

Cited Authors

  • Stamler, JS; Hess, DT

Published Date

  • November 2010

Published In

Volume / Issue

  • 12 / 11

Start / End Page

  • 1024 - 1026

PubMed ID

  • 20972426

Pubmed Central ID

  • 20972426

Electronic International Standard Serial Number (EISSN)

  • 1476-4679

Digital Object Identifier (DOI)

  • 10.1038/ncb1110-1024


  • eng

Conference Location

  • England