The use of antiepileptic drugs in bipolar disorders: a review based on evidence from controlled trials.
Journal Article (Journal Article;Review)
Antiepileptic drugs (AEDs) have diverse psychotropic profiles. Some AEDs have proven to be efficacious in the treatment of mood disorders, especially bipolar disorder. Others are ineffective as primary treatments but may be useful adjuncts for mood disorders or comorbid conditions. Valproate (acute mania and mixed episodes), carbamazepine (acute mania and mixed episodes), and lamotrigine (maintenance to delay recurrence) have United States Food and Drug Administration indications for the treatment of bipolar disorder. This article provides an overview of data on the use of AEDs in bipolar disorder, including acute mania and depression, prophylaxis, and rapid cycling.
Full Text
Duke Authors
Cited Authors
- Weisler, RH; Cutler, AJ; Ballenger, JC; Post, RM; Ketter, TA
Published Date
- October 2006
Published In
Volume / Issue
- 11 / 10
Start / End Page
- 788 - 799
PubMed ID
- 17008822
Pubmed Central ID
- 17008822
International Standard Serial Number (ISSN)
- 1092-8529
Digital Object Identifier (DOI)
- 10.1017/s1092852900014917
Language
- eng
Conference Location
- United States