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Change in intrathoracic impedance measures during acute decompensated heart failure admission: results from the Diagnostic Data for Discharge in Heart Failure Patients (3D-HF) Pilot Study.

Publication ,  Journal Article
Whellan, DJ; Droogan, CJ; Fitzpatrick, J; Adams, S; McCarey, MM; Andrel, J; Mather, P; Rubin, S; Bonita, R; Keith, S
Published in: J Card Fail
February 2012

BACKGROUND: Despite the high number of admissions for acute decompensated heart failure (ADHF), there are no specific criteria for discharge readiness. A number of patients have implantable devices that might provide data to assist in determining readiness for discharge. METHODS AND RESULTS: The 3D-HF (Diagnostic Data for Discharge in Heart Failure Patients) study was a prospective observational pilot study enrolling HF patients with Optivol-capable cardiac devices within 48 hours of a hospital admission characterized by worsening HF symptoms. The primary end point was the difference in times from admission to 50% improvement in impedance and to when patient was medically ready for discharge. The nonparametric sign test was used to determine if the difference was significant. A total of 20 subjects were enrolled over a 24-month period. The median ADHF length of stay was 7 days. Of the 20 subjects, 18 achieved the intrathoracic impedance improvement threshold before discharge. The time to reach the threshold for improvement was 2.5 days (interquartile range 2.0-6.0). The difference between days to 50% impedance and days to provider's discharge decision was 3.0 (P = .0072). CONCLUSIONS: Intrathoracic impedance changes were evident over a short duration in the majority of patients admitted for ADHF and may be a potential criterion for discharge readiness.

Duke Scholars

Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

February 2012

Volume

18

Issue

2

Start / End Page

107 / 112

Location

United States

Related Subject Headings

  • Weight Loss
  • Treatment Outcome
  • Severity of Illness Index
  • Prospective Studies
  • Pilot Projects
  • Pennsylvania
  • Patient Discharge
  • Male
  • Length of Stay
  • Humans
 

Citation

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Whellan, D. J., Droogan, C. J., Fitzpatrick, J., Adams, S., McCarey, M. M., Andrel, J., … Keith, S. (2012). Change in intrathoracic impedance measures during acute decompensated heart failure admission: results from the Diagnostic Data for Discharge in Heart Failure Patients (3D-HF) Pilot Study. J Card Fail, 18(2), 107–112. https://doi.org/10.1016/j.cardfail.2011.10.017
Whellan, David J., Christopher J. Droogan, James Fitzpatrick, Suzanne Adams, Melissa M. McCarey, Jocelyn Andrel, Paul Mather, Sharon Rubin, Raphael Bonita, and Scott Keith. “Change in intrathoracic impedance measures during acute decompensated heart failure admission: results from the Diagnostic Data for Discharge in Heart Failure Patients (3D-HF) Pilot Study.J Card Fail 18, no. 2 (February 2012): 107–12. https://doi.org/10.1016/j.cardfail.2011.10.017.
Whellan, David J., et al. “Change in intrathoracic impedance measures during acute decompensated heart failure admission: results from the Diagnostic Data for Discharge in Heart Failure Patients (3D-HF) Pilot Study.J Card Fail, vol. 18, no. 2, Feb. 2012, pp. 107–12. Pubmed, doi:10.1016/j.cardfail.2011.10.017.
Whellan DJ, Droogan CJ, Fitzpatrick J, Adams S, McCarey MM, Andrel J, Mather P, Rubin S, Bonita R, Keith S. Change in intrathoracic impedance measures during acute decompensated heart failure admission: results from the Diagnostic Data for Discharge in Heart Failure Patients (3D-HF) Pilot Study. J Card Fail. 2012 Feb;18(2):107–112.
Journal cover image

Published In

J Card Fail

DOI

EISSN

1532-8414

Publication Date

February 2012

Volume

18

Issue

2

Start / End Page

107 / 112

Location

United States

Related Subject Headings

  • Weight Loss
  • Treatment Outcome
  • Severity of Illness Index
  • Prospective Studies
  • Pilot Projects
  • Pennsylvania
  • Patient Discharge
  • Male
  • Length of Stay
  • Humans