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Case report: treatment of chronic osteomyelitis.

Publication ,  Journal Article
Wolfe, CR
Published in: Clin Infect Dis
June 2011

Presented is a case of chronic methicillin-resistant Staphylococcus aureus osteomyelitis, which was unsuccessfully treated with multiple courses of debridement and potent antibiotic therapies. Amputation of the patient's lower limb was believed to be the only option remaining. A compassionate access program, with approval from the US Food and Drug Administration and the institutional review board, enabled the patient to undergo a course of treatment with oral fusidic acid (CEM-102). The patient tolerated the drug well, with no significant toxicities noted to date. His infection improved rapidly, his flap healed, he has returned to work part-time, and he continues to take daily suppressive doses of oral CEM-102.

Duke Scholars

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

June 2011

Volume

52 Suppl 7

Start / End Page

S538 / S541

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Staphylococcal Infections
  • Osteomyelitis
  • Middle Aged
  • Microbiology
  • Methicillin-Resistant Staphylococcus aureus
  • Male
  • Humans
  • Fusidic Acid
  • Debridement
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Wolfe, C. R. (2011). Case report: treatment of chronic osteomyelitis. Clin Infect Dis, 52 Suppl 7, S538–S541. https://doi.org/10.1093/cid/cir169
Wolfe, Cameron R. “Case report: treatment of chronic osteomyelitis.Clin Infect Dis 52 Suppl 7 (June 2011): S538–41. https://doi.org/10.1093/cid/cir169.
Wolfe CR. Case report: treatment of chronic osteomyelitis. Clin Infect Dis. 2011 Jun;52 Suppl 7:S538–41.
Wolfe, Cameron R. “Case report: treatment of chronic osteomyelitis.Clin Infect Dis, vol. 52 Suppl 7, June 2011, pp. S538–41. Pubmed, doi:10.1093/cid/cir169.
Wolfe CR. Case report: treatment of chronic osteomyelitis. Clin Infect Dis. 2011 Jun;52 Suppl 7:S538–S541.
Journal cover image

Published In

Clin Infect Dis

DOI

EISSN

1537-6591

Publication Date

June 2011

Volume

52 Suppl 7

Start / End Page

S538 / S541

Location

United States

Related Subject Headings

  • Treatment Outcome
  • Staphylococcal Infections
  • Osteomyelitis
  • Middle Aged
  • Microbiology
  • Methicillin-Resistant Staphylococcus aureus
  • Male
  • Humans
  • Fusidic Acid
  • Debridement