Case report: treatment of chronic osteomyelitis.

Journal Article (Journal Article)

Presented is a case of chronic methicillin-resistant Staphylococcus aureus osteomyelitis, which was unsuccessfully treated with multiple courses of debridement and potent antibiotic therapies. Amputation of the patient's lower limb was believed to be the only option remaining. A compassionate access program, with approval from the US Food and Drug Administration and the institutional review board, enabled the patient to undergo a course of treatment with oral fusidic acid (CEM-102). The patient tolerated the drug well, with no significant toxicities noted to date. His infection improved rapidly, his flap healed, he has returned to work part-time, and he continues to take daily suppressive doses of oral CEM-102.

Full Text

Duke Authors

Cited Authors

  • Wolfe, CR

Published Date

  • June 2011

Published In

Volume / Issue

  • 52 Suppl 7 /

Start / End Page

  • S538 - S541

PubMed ID

  • 21546631

Electronic International Standard Serial Number (EISSN)

  • 1537-6591

Digital Object Identifier (DOI)

  • 10.1093/cid/cir169


  • eng

Conference Location

  • United States