Osteoid osteoma and osteoblastoma.

Journal Article (Journal Article;Review)

Osteoid osteoma and osteoblastoma are commonly seen benign osteogenic bone neoplasms. Both tumors are typically seen in the second decade of life, with a notable predilection in males. Histologically, these tumors resemble each other, with characteristically increased osteoid tissue formation surrounded by vascular fibrous stroma and perilesional sclerosis. However, osteoblastomas are larger than osteoid osteomas, and they exhibit greater osteoid production and vascularity. Clinically, osteoid osteoma most commonly occurs in the long bones (eg, femur, tibia). The lesions cause night pain that is relieved with nonsteroidal anti-inflammatory drugs (NSAIDs). Osteoblastoma is most frequently located in the axial skeleton, and the pain is usually not worse at night and is less likely to be relieved with NSAIDs. Osteoblastoma can be locally aggressive; osteoid osteoma lacks growth potential. Osteoid osteoma may be managed nonsurgically with NSAIDs. When surgery is required, minimally invasive methods (eg, CT-guided excision, radiofrequency ablation) are preferred. Osteoblastoma has a higher rate of recurrence than does osteoid osteoma, and patients must be treated surgically with intralesional curettage or en bloc resection.

Full Text

Duke Authors

Cited Authors

  • Atesok, KI; Alman, BA; Schemitsch, EH; Peyser, A; Mankin, H

Published Date

  • November 2011

Published In

Volume / Issue

  • 19 / 11

Start / End Page

  • 678 - 689

PubMed ID

  • 22052644

International Standard Serial Number (ISSN)

  • 1067-151X

Digital Object Identifier (DOI)

  • 10.5435/00124635-201111000-00004


  • eng

Conference Location

  • United States