The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration.

Journal Article (Journal Article;Review)

Precompetitive collaboration is a growing driver for innovation and increased productivity in biomedical science and drug development. The Biomarkers Consortium, a public-private platform for precompetitive collaboration specific to biomarkers, demonstrated that adiponectin has potential utility as a predictor of metabolic responses to peroxisome proliferator-activated receptor (PPAR) agonists in individuals with type 2 diabetes. Despite the challenges overcome by this project, the most important lesson learned is that cross-company precompetitive collaboration is a feasible robust approach to biomarker qualification.

Full Text

Duke Authors

Cited Authors

  • Wagner, JA; Prince, M; Wright, EC; Ennis, MM; Kochan, J; Nunez, DJR; Schneider, B; Wang, M-D; Chen, Y; Ghosh, S; Musser, BJ; Vassileva, MT

Published Date

  • May 2010

Published In

Volume / Issue

  • 87 / 5

Start / End Page

  • 539 - 542

PubMed ID

  • 20407460

Electronic International Standard Serial Number (EISSN)

  • 1532-6535

Digital Object Identifier (DOI)

  • 10.1038/clpt.2009.227


  • eng

Conference Location

  • United States