The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration.
Precompetitive collaboration is a growing driver for innovation and increased productivity in biomedical science and drug development. The Biomarkers Consortium, a public-private platform for precompetitive collaboration specific to biomarkers, demonstrated that adiponectin has potential utility as a predictor of metabolic responses to peroxisome proliferator-activated receptor (PPAR) agonists in individuals with type 2 diabetes. Despite the challenges overcome by this project, the most important lesson learned is that cross-company precompetitive collaboration is a feasible robust approach to biomarker qualification.
Wagner, JA; Prince, M; Wright, EC; Ennis, MM; Kochan, J; Nunez, DJR; Schneider, B; Wang, M-D; Chen, Y; Ghosh, S; Musser, BJ; Vassileva, MT
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