The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration.
Publication
, Journal Article
Wagner, JA; Prince, M; Wright, EC; Ennis, MM; Kochan, J; Nunez, DJR; Schneider, B; Wang, M-D; Chen, Y; Ghosh, S; Musser, BJ; Vassileva, MT
Published in: Clin Pharmacol Ther
May 2010
Precompetitive collaboration is a growing driver for innovation and increased productivity in biomedical science and drug development. The Biomarkers Consortium, a public-private platform for precompetitive collaboration specific to biomarkers, demonstrated that adiponectin has potential utility as a predictor of metabolic responses to peroxisome proliferator-activated receptor (PPAR) agonists in individuals with type 2 diabetes. Despite the challenges overcome by this project, the most important lesson learned is that cross-company precompetitive collaboration is a feasible robust approach to biomarker qualification.
Duke Scholars
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Published In
Clin Pharmacol Ther
DOI
EISSN
1532-6535
Publication Date
May 2010
Volume
87
Issue
5
Start / End Page
539 / 542
Location
United States
Related Subject Headings
- Randomized Controlled Trials as Topic
- Pharmacology & Pharmacy
- Humans
- Economic Competition
- Drug Industry
- Drug Design
- Drug Delivery Systems
- Cooperative Behavior
- Biomarkers
- Animals
Citation
APA
Chicago
ICMJE
MLA
NLM
Wagner, J. A., Prince, M., Wright, E. C., Ennis, M. M., Kochan, J., Nunez, D. J. R., … Vassileva, M. T. (2010). The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration. Clin Pharmacol Ther, 87(5), 539–542. https://doi.org/10.1038/clpt.2009.227
Wagner, J. A., M. Prince, E. C. Wright, M. M. Ennis, J. Kochan, D. J. R. Nunez, B. Schneider, et al. “The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration.” Clin Pharmacol Ther 87, no. 5 (May 2010): 539–42. https://doi.org/10.1038/clpt.2009.227.
Wagner JA, Prince M, Wright EC, Ennis MM, Kochan J, Nunez DJR, et al. The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration. Clin Pharmacol Ther. 2010 May;87(5):539–42.
Wagner, J. A., et al. “The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration.” Clin Pharmacol Ther, vol. 87, no. 5, May 2010, pp. 539–42. Pubmed, doi:10.1038/clpt.2009.227.
Wagner JA, Prince M, Wright EC, Ennis MM, Kochan J, Nunez DJR, Schneider B, Wang M-D, Chen Y, Ghosh S, Musser BJ, Vassileva MT. The Biomarkers Consortium: practice and pitfalls of open-source precompetitive collaboration. Clin Pharmacol Ther. 2010 May;87(5):539–542.
Published In
Clin Pharmacol Ther
DOI
EISSN
1532-6535
Publication Date
May 2010
Volume
87
Issue
5
Start / End Page
539 / 542
Location
United States
Related Subject Headings
- Randomized Controlled Trials as Topic
- Pharmacology & Pharmacy
- Humans
- Economic Competition
- Drug Industry
- Drug Design
- Drug Delivery Systems
- Cooperative Behavior
- Biomarkers
- Animals