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agr-Amanitin Tolerance in Mycophagous Drosophila.

Publication ,  Journal Article
Jaenike, J; Grimaldi, DA; Sluder, AE; Greenleaf, AL
Published in: Science
July 8, 1983

Six species of Drosophila were tested for tolerance to the mushroom toxin alpha-amanitin, a potent inhibitor of RNA polymerase II. Three nonmycophagous species-D. melanogaster, D. immigrans, and D. pseudoobscura-showed very low survival and long development times in the presence of amanitin. Three mycophagous species-D. putrida, D. recens, and D. tripunctata-showed little or no sensitivity. Analysis in vitro indicated that this tolerance is not based on alteration of the molecular structure of RNA polymerase II.

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Published In

Science

DOI

ISSN

0036-8075

Publication Date

July 8, 1983

Volume

221

Issue

4606

Start / End Page

165 / 167

Location

United States

Related Subject Headings

  • General Science & Technology
 

Citation

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Jaenike, J., Grimaldi, D. A., Sluder, A. E., & Greenleaf, A. L. (1983). agr-Amanitin Tolerance in Mycophagous Drosophila. Science, 221(4606), 165–167. https://doi.org/10.1126/science.221.4606.165
Jaenike, J., D. A. Grimaldi, A. E. Sluder, and A. L. Greenleaf. “agr-Amanitin Tolerance in Mycophagous Drosophila.Science 221, no. 4606 (July 8, 1983): 165–67. https://doi.org/10.1126/science.221.4606.165.
Jaenike J, Grimaldi DA, Sluder AE, Greenleaf AL. agr-Amanitin Tolerance in Mycophagous Drosophila. Science. 1983 Jul 8;221(4606):165–7.
Jaenike, J., et al. “agr-Amanitin Tolerance in Mycophagous Drosophila.Science, vol. 221, no. 4606, July 1983, pp. 165–67. Pubmed, doi:10.1126/science.221.4606.165.
Jaenike J, Grimaldi DA, Sluder AE, Greenleaf AL. agr-Amanitin Tolerance in Mycophagous Drosophila. Science. 1983 Jul 8;221(4606):165–167.
Journal cover image

Published In

Science

DOI

ISSN

0036-8075

Publication Date

July 8, 1983

Volume

221

Issue

4606

Start / End Page

165 / 167

Location

United States

Related Subject Headings

  • General Science & Technology