Image noise, resolution, and lesion detectability in single photon emission ct


Journal Article

Single Photon Emission Computed Tomography (SPECT) based on rotational scintillation gamma cameras in combination with “filtered back-projection allows full 3-D imaging of isotope uptake in an organ volume. (1, 2,3,4) This paper treats the physical dependence of lesion detectability in SPECT imaging on the lesion uptake, lesion size, object size, and the number of photons collected. The lesion contrast depends on both camera resolution and reconstruction filtering. The relative photon-limited image noise is proportional to the three halves power of the number of linear samples covering the object, inversely proportional to the sguare root of the number of photons collected, and is also affected by the reconstruction filter chosen. Based on signal-to-noise analysis, the total number of counts necessary for lesion detection is determined. Copyright © 1982 by The Institute of Electrical and Electronics Engineers, Inc.

Full Text

Duke Authors

Cited Authors

  • Bin Lim, C; Sun Han, K; Hawman, EG; Jaszczak, RJ

Published Date

  • January 1, 1982

Published In

Volume / Issue

  • 29 / 1

Start / End Page

  • 500 - 505

Electronic International Standard Serial Number (EISSN)

  • 1558-1578

International Standard Serial Number (ISSN)

  • 0018-9499

Digital Object Identifier (DOI)

  • 10.1109/TNS.1982.4335895

Citation Source

  • Scopus