A new treatment algorithm for posttraumatic stress disorder
Treating PTSD requires selecting an appropriate first-line treatment, deciding on length of treatment, and knowing when and how to change to another approach. The algorithm presented in this article provides sequential choices to decide whether to persist longer at the highest tolerated dose, augment with a second agent, or switch to another treatment. There is a need to evaluate levels of response (full, partial, or nonresponse), as well as to decide whether partial response is generalized to all PTSD symptoms or limited to select symptoms. Treatment strategies may then be based on which scenario is present. Issues of comorbidity and diagnostic reevaluation must be considered as well.
Davidson, J; Bernik, M; Connor, KM; Friedman, MJ; Jobson, KO; Kim, Y; Lecrubier, Y; Ma, H; Njenga, F; Stein, DJ; Zohar, J
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