Chronic pain and depression. III. Family history study of depression and alcoholism in chronic low back pain patients.


Journal Article

In an attempt to unravel the relationship between chronic pain and depression, the authors studied the incidence of depression, alcoholism, and chronic pain in first degree relatives of 100 chronic pain patients with and without depression. A higher incidence of major depression was found in first degree relatives of those patients with depression than those without depression. Familial incidence of alcohol dependence was similar in both groups of patients. These findings confirm an earlier report and raise questions about the notion of considering chronic pain simply as a variant of depression and suggest the possibility that the occurrence of major depression in chronic back pain might be related to genetic vulnerability to depression in these patients.

Full Text

Duke Authors

Cited Authors

  • France, RD; Krishnan, KR; Trainor, M

Published Date

  • February 1, 1986

Published In

Volume / Issue

  • 24 / 2

Start / End Page

  • 185 - 190

PubMed ID

  • 2938057

Pubmed Central ID

  • 2938057

International Standard Serial Number (ISSN)

  • 0304-3959

Digital Object Identifier (DOI)

  • 10.1016/0304-3959(86)90040-0


  • eng

Conference Location

  • United States