Can topical ketorolac 0.5% improve the function of Ahmed® glaucoma drainage devices?

Journal Article (Journal Article)

BACKGROUND AND OBJECTIVE: To determine whether postoperative use of topical ketorolac tromethamine 0.5% affects intraocular pressure (IOP) following Ahmed glaucoma drainage device (New World Medical, Inc., Rancho Cucamonga, CA) implantation. PATIENTS AND METHODS: Patients undergoing Ahmed implantation at the University of Michigan from January 2002 to June 2008 were reviewed. Fourteen eyes received ketorolac after surgery; 50 eyes did not. Preoperative and postoperative IOP and glaucoma medications were recorded for both groups; the two-sided Student's t test was used to compare these parameters. RESULTS: Mean preoperative IOP was similar in the two groups (35.1 ± 11.9 vs 37.0 ± 12.2 mm Hg; P = .60). At postoperative month 6, the ketorolac group had significantly lower IOP compared with the no ketorolac group (13.1 ± 3.7 vs 19.5 ± 9.3 mm Hg, respectively; P = .0003). There was no difference in the number of glaucoma medications postoperatively between the two groups. CONCLUSION: Ketorolac may lead to lower postoperative IOP following Ahmed implantation.

Full Text

Duke Authors

Cited Authors

  • Scott, GR; Weizer, JS; Moroi, SE; Bruno, CA; Musch, DC; Niziol, LM; Lee, PP; Stein, JD

Published Date

  • 2011

Published In

Volume / Issue

  • 42 / 3

Start / End Page

  • 190 - 195

PubMed ID

  • 21449531

Pubmed Central ID

  • PMC3343136

Electronic International Standard Serial Number (EISSN)

  • 1938-2375

Digital Object Identifier (DOI)

  • 10.3928/15428877-20110324-03


  • eng

Conference Location

  • United States