Evidence for formation of superoxide and formate radicals in Methanobacterium formicicum.
Journal Article (Journal Article)
Using spin labeling and spin trapping techniques in combination with electron paramagnetic resonance spectrometry, we have detected the formation of superoxide by whole cells of Methanobacterium formicicum under aerobic conditions in the presence and absence of sodium formate. Rates of superoxide generation have been estimated. The formation of additional free radical species, including formate, was observed. Production of these and other free radicals resulted in lipid peroxidation and concomitant cell damage.
Full Text
Duke Authors
Cited Authors
- Barber, MJ; Rosen, GM; Siegel, LM; Rauckman, EJ
Published Date
- March 1983
Published In
Volume / Issue
- 153 / 3
Start / End Page
- 1282 - 1286
PubMed ID
- 6298181
Pubmed Central ID
- PMC221774
International Standard Serial Number (ISSN)
- 0021-9193
Digital Object Identifier (DOI)
- 10.1128/jb.153.3.1282-1286.1983
Language
- eng
Conference Location
- United States