Clinical applications of electroconvulsive therapy and transcranial magnetic stimulation for the treatment of major depressive disorder: A critical review


Journal Article (Review)

Depression is a common and debilitating psychiatric disorder that is often unable to be effectively treated with pharmacotherapeutic agents alone. Electroconvulsive therapy (ECT) and transcranial magnetic stimulation (TMS) are among several somatic therapies available for the treatment of major depression. The purpose of this article is to synthesize current information on ECT and repetitive TMS as treatments for pharmacotherapy-resistant major depression regarding its use in neuropsychiatric clinical practice. The current psychiatric literature indicates that both ECT and TMS are effective antidepressant treatments. ECT is a safe and highly effective treatment for depression. The literature also illustrates that TMS has a favorable side-effect profile, excellent tolerability and modest efficacy. To date, additional research is being conducted to further enhance ECT and TMS treatment, and to further define their role in treatment algorithms. © 2012 Future Medicine Ltd.

Full Text

Duke Authors

Cited Authors

  • Baker, PL; Trevino, K; McClintock, SM; Wani, A; Husain, MM

Published Date

  • October 1, 2012

Published In

Volume / Issue

  • 2 / 5

Start / End Page

  • 443 - 451

Electronic International Standard Serial Number (EISSN)

  • 1758-2016

International Standard Serial Number (ISSN)

  • 1758-2008

Digital Object Identifier (DOI)

  • 10.2217/npy.12.52

Citation Source

  • Scopus