Heart failure in elderly patients: distinctive features and unresolved issues.


Journal Article (Review)

The prevalence of heart failure (HF) increases with age. While clinical trials suggest that contemporary evidence-based HF therapies have reduced morbidity and mortality, these trials largely excluded the elderly. Questions remain regarding the clinical characteristics of elderly HF patients and the impact of contemporary therapies on their outcomes. This review presents the epidemiology of HF in the elderly and summarizes the data on the pathophysiology of the ageing heart. The clinical characteristics, treatment patterns, and outcomes of elderly HF patients are explored. Finally, the main gaps regarding HF therapies in the elderly and the opportunities for future trials are highlighted.

Full Text

Duke Authors

Cited Authors

  • Lazzarini, V; Mentz, RJ; Fiuzat, M; Metra, M; O'Connor, CM

Published Date

  • July 2013

Published In

Volume / Issue

  • 15 / 7

Start / End Page

  • 717 - 723

PubMed ID

  • 23429975

Pubmed Central ID

  • 23429975

Electronic International Standard Serial Number (EISSN)

  • 1879-0844

Digital Object Identifier (DOI)

  • 10.1093/eurjhf/hft028


  • eng

Conference Location

  • England