Light uncages a copper complex to induce nonapoptotic cell death.
Journal Article (Journal Article)
Cu3G is a Cu(II) complex of a photoactive tetradentate ligand that is cleaved upon UV irradiation to release Cu. Here we show that the cytotoxicity of Cu3G increases in response to brief UV stimulation to result in extensive cytoplasmic vacuolization that is indicative of nonapoptotic cell death.
Full Text
Duke Authors
Cited Authors
- Kumbhar, AA; Franks, AT; Butcher, RJ; Franz, KJ
Published Date
- March 2013
Published In
Volume / Issue
- 49 / 24
Start / End Page
- 2460 - 2462
PubMed ID
- 23417227
Electronic International Standard Serial Number (EISSN)
- 1364-548X
International Standard Serial Number (ISSN)
- 1359-7345
Digital Object Identifier (DOI)
- 10.1039/c3cc38927h
Language
- eng