Regional blood flow in avian sarcoma virus (ASV)-induced brain tumors.

Journal Article (Journal Article)

Regional blood flow (F) was measured in avian sarcoma virus (ASV)-induced brain tumors in rats. Blood flow was variable in individual as well as different tumors; tumor F did not correlate with histologic classification, tumor size, central versus peripheral tumor regions, intraparenchymal location, cell density, or specific cytologic characteristics. Low values of F did correlate with tumor necrosis and hydrocephalus; high values of F correlated with tumorous invasion or association with choroid plexus. Mean tumor F was not significantly different from that of the same anatomic, tumor-free brain region of the contralateral hemisphere, but F in brain tissue adjacent to the tumor was depressed significantly. Depression of F was observed in tumor-free cortex and corpus callosum, especially in the hemisphere ipsilateral to the main tumor mass and in those animals with hydrocephalus.

Full Text

Duke Authors

Cited Authors

  • Groothuis, D; Blasberg, RG; Molnar, P; Bigner, D; Fenstermacher, JD

Published Date

  • June 1, 1983

Published In

Volume / Issue

  • 33 / 6

Start / End Page

  • 686 - 696

PubMed ID

  • 6302562

International Standard Serial Number (ISSN)

  • 0028-3878

Digital Object Identifier (DOI)

  • 10.1212/wnl.33.6.686


  • eng

Conference Location

  • United States