Early life predictors of atrial fibrillation-related mortality: evidence from the health and retirement study.

Journal Article (Journal Article)

Prior research found that Americans born in 6 southeastern states (the AF-risk zone) had elevated risk of AF-related mortality, but no mechanisms were identified. We hypothesized the association between AF-related mortality and AF-risk zone birth is explained by indicators of childhood social disadvantage or adult risk factors. In 24,323 participants in the US Health and Retirement Study, we found that birth in the AF-risk zone was significantly associated with hazard of AF-related mortality. Among whites, the relationship was specific to place of birth, rather than place of adult residence. Neither paternal education nor subjectively assessed childhood SES predicted AF-related mortality. Conventional childhood and adult cardiovascular risk factors did not explain the association between place of birth and AF-related mortality.

Full Text

Duke Authors

Cited Authors

  • Glymour, MM; Benjamin, EJ; Kosheleva, A; Gilsanz, P; Curtis, LH; Patton, KK

Published Date

  • May 2013

Published In

Volume / Issue

  • 21 /

Start / End Page

  • 133 - 139

PubMed ID

  • 23454734

Pubmed Central ID

  • PMC3640834

Electronic International Standard Serial Number (EISSN)

  • 1873-2054

Digital Object Identifier (DOI)

  • 10.1016/j.healthplace.2012.12.008


  • eng

Conference Location

  • England