Willingness-to-pay and preferences for warfarin pharmacogenetic testing in Chinese warfarin patients and the Chinese general public


Journal Article

Aim: Genetic factors have been found to affect warfarin maintenance dose and a key factor for the successful clinical implementation of warfarin pharmacogenetic testing (WPGT) is economic sustainability. We aimed to estimate the willingness-to-pay (WTP) and preferences for WPGT in Singaporean Chinese subjects. Methods & subjects: A total of 197 warfarin patients and 187 members of the public completed a questionnaire. The discrete choice methodology was used and the choice model was estimated using hierarchical Bayes. Marginal WTP, attribute importance and WTP for three hypothetical WPGTs were calculated from the estimated utilities. Results: Both patients and the public placed most emphasis on side effects, followed by cost, number of International Normalized Ratio tests and 'nature of test. WTP for WPGT ranged from S160 to S730. Conclusion: WPGTs are likely to be economically sustainable. © 2013 Future Medicine Ltd.

Full Text

Duke Authors

Cited Authors

  • Chan, SL; Wen Low, JJ; Lim, YW; Finkelstein, E; Farooqui, MA; Chia, KS; Wee, HL

Published Date

  • March 11, 2013

Published In

Volume / Issue

  • 10 / 2

Start / End Page

  • 127 - 137

Electronic International Standard Serial Number (EISSN)

  • 1744-828X

International Standard Serial Number (ISSN)

  • 1741-0541

Digital Object Identifier (DOI)

  • 10.2217/pme.12.124

Citation Source

  • Scopus