Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation.
Publication
, Journal Article
Deeg, HJ; Lum, LG; Sanders, J; Levy, GJ; Sullivan, KM; Beatty, P; Thomas, ED; Storb, R
Published in: Transplantation
May 1986
Chronic mucocutaneous candidiasis (CMC) is typically associated with the inability of T lymphocytes to proliferate and produce lymphokines in response to Candida antigen. A 7-year-old girl with CMC developed severe aplastic anemia and, after conditioning with cyclophosphamide, 200 mg/kg, underwent bone marrow transplantation from her HLA-identical sister. Engraftment was prompt and complete. The patient is surviving more than 3 years after transplantation with normal donor-derived hemopoiesis and immune function. Manifestations of CMC have resolved completely and she has not received antifungal therapy for more than 2 years.
Duke Scholars
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Published In
Transplantation
DOI
ISSN
0041-1337
Publication Date
May 1986
Volume
41
Issue
5
Start / End Page
583 / 586
Location
United States
Related Subject Headings
- Surgery
- Lymphocyte Activation
- Hypersensitivity, Delayed
- Humans
- Hematopoiesis
- Female
- Child
- Candidiasis, Chronic Mucocutaneous
- Candidiasis
- Bone Marrow Transplantation
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APA
Chicago
ICMJE
MLA
NLM
Deeg, H. J., Lum, L. G., Sanders, J., Levy, G. J., Sullivan, K. M., Beatty, P., … Storb, R. (1986). Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation. Transplantation, 41(5), 583–586. https://doi.org/10.1097/00007890-198605000-00006
Deeg, H. J., L. G. Lum, J. Sanders, G. J. Levy, K. M. Sullivan, P. Beatty, E. D. Thomas, and R. Storb. “Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation.” Transplantation 41, no. 5 (May 1986): 583–86. https://doi.org/10.1097/00007890-198605000-00006.
Deeg HJ, Lum LG, Sanders J, Levy GJ, Sullivan KM, Beatty P, et al. Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation. Transplantation. 1986 May;41(5):583–6.
Deeg, H. J., et al. “Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation.” Transplantation, vol. 41, no. 5, May 1986, pp. 583–86. Pubmed, doi:10.1097/00007890-198605000-00006.
Deeg HJ, Lum LG, Sanders J, Levy GJ, Sullivan KM, Beatty P, Thomas ED, Storb R. Severe aplastic anemia associated with chronic mucocutaneous candidiasis. Immunologic and hematologic reconstitution after allogeneic bone marrow transplantation. Transplantation. 1986 May;41(5):583–586.
Published In
Transplantation
DOI
ISSN
0041-1337
Publication Date
May 1986
Volume
41
Issue
5
Start / End Page
583 / 586
Location
United States
Related Subject Headings
- Surgery
- Lymphocyte Activation
- Hypersensitivity, Delayed
- Humans
- Hematopoiesis
- Female
- Child
- Candidiasis, Chronic Mucocutaneous
- Candidiasis
- Bone Marrow Transplantation