Allogeneic marrow transplantation for acute leukemia in relapse.
Publication
, Journal Article
Badger, C; Buckner, CD; Thomas, ED; Clift, RA; Sanders, JE; Stewart, PS; Storb, R; Sullivan, KM; Shulman, H; Flournoy, N
Published in: Leuk Res
1982
The results of allogeneic marrow transplantation in 75 patients with acute lymphoblastic leukemia and 63 patients with acute non-lymphoblastic leukemia in relapse are reviewed. The effects of various chemotherapeutic regimens added to the basic regimen of cyclophosphamide (Cy) 60 mg/kg given on each of two successive days followed by 1000 rad of total body irradiation (TBI) were evaluated. The regimens tested were dimethylbusulphan (DMB), 1,3-bis(2-chlorethyl)-1-nitrosourea (BCNU) and daunorubicin. Seventeen of 138 patients are alive between three and nine and a half years from transplantation. The addition of other chemotherapeutic agents to th basic Cy and TBI regimen did not decrease relapse frequency or prolong survival.
Duke Scholars
Published In
Leuk Res
DOI
ISSN
0145-2126
Publication Date
1982
Volume
6
Issue
3
Start / End Page
383 / 387
Location
England
Related Subject Headings
- Whole-Body Irradiation
- Recurrence
- Middle Aged
- Leukemia, Lymphoid
- Leukemia
- Infant
- Immunology
- Humans
- Follow-Up Studies
- Cyclophosphamide
Citation
APA
Chicago
ICMJE
MLA
NLM
Badger, C., Buckner, C. D., Thomas, E. D., Clift, R. A., Sanders, J. E., Stewart, P. S., … Flournoy, N. (1982). Allogeneic marrow transplantation for acute leukemia in relapse. Leuk Res, 6(3), 383–387. https://doi.org/10.1016/0145-2126(82)90101-1
Badger, C., C. D. Buckner, E. D. Thomas, R. A. Clift, J. E. Sanders, P. S. Stewart, R. Storb, K. M. Sullivan, H. Shulman, and N. Flournoy. “Allogeneic marrow transplantation for acute leukemia in relapse.” Leuk Res 6, no. 3 (1982): 383–87. https://doi.org/10.1016/0145-2126(82)90101-1.
Badger C, Buckner CD, Thomas ED, Clift RA, Sanders JE, Stewart PS, et al. Allogeneic marrow transplantation for acute leukemia in relapse. Leuk Res. 1982;6(3):383–7.
Badger, C., et al. “Allogeneic marrow transplantation for acute leukemia in relapse.” Leuk Res, vol. 6, no. 3, 1982, pp. 383–87. Pubmed, doi:10.1016/0145-2126(82)90101-1.
Badger C, Buckner CD, Thomas ED, Clift RA, Sanders JE, Stewart PS, Storb R, Sullivan KM, Shulman H, Flournoy N. Allogeneic marrow transplantation for acute leukemia in relapse. Leuk Res. 1982;6(3):383–387.
Published In
Leuk Res
DOI
ISSN
0145-2126
Publication Date
1982
Volume
6
Issue
3
Start / End Page
383 / 387
Location
England
Related Subject Headings
- Whole-Body Irradiation
- Recurrence
- Middle Aged
- Leukemia, Lymphoid
- Leukemia
- Infant
- Immunology
- Humans
- Follow-Up Studies
- Cyclophosphamide