Allogeneic marrow transplantation for acute non-lymphoblastic leukemia in relapse using fractionated total body irradiation.

Journal Article (Journal Article)

Twenty-three patients with acute non-lymphoblastic leukemia in relapse were treated with cyclophosphamide, fractionated total body irradiation (200 rad/day for six days) and allogeneic marrow transplantation. Six patients are alive in remission 756-1306 days following transplantation. One patient died of infection on day 17 without evidence of engraftment; all others achieved sustained engraftment. Eight patients died of recurrent leukemia, four of interstitial pneumonitis, two of infection, one of veno-occlusive disease of the liver and one of cardiac failure. The median survival time was 181 days.

Full Text

Duke Authors

Cited Authors

  • Buckner, CD; Clift, RA; Thomas, ED; Sanders, JE; Stewart, PS; Storb, R; Sullivan, KM; Hackman, R

Published Date

  • 1982

Published In

Volume / Issue

  • 6 / 3

Start / End Page

  • 389 - 394

PubMed ID

  • 6750251

International Standard Serial Number (ISSN)

  • 0145-2126

Digital Object Identifier (DOI)

  • 10.1016/0145-2126(82)90102-3


  • eng

Conference Location

  • England