Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization.
Publication
, Journal Article
Chu, FF; Rohan de Silva, HA; Esworthy, RS; Boteva, KK; Walters, CE; Roses, A; Rao, PN; Pettenati, MJ
Published in: Genomics
March 1996
We have isolated a 3.3-kb DNA containing the two exons and a 2.6-kb intron of the human CPX2 gene. This gene encodes the intestinal isoenzyme of glutathione peroxidase, GSHPx-GI. Consistent signals were detected at 14q24.1 when this DNA was used as a probe for fluorescence in situ hybridization on metaphase chromosomes. Based on either single-stranded conformation polymorphism or sequencing analysis, two sites containing DNA polymorphism were found in the intron: the 5' end had a single A/T alteration, and the 3' end had a microsatellite of TC repeats.
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Published In
Genomics
DOI
EISSN
1089-8646
ISSN
0888-7543
Publication Date
March 1996
Volume
32
Issue
2
Start / End Page
272 / 276
Related Subject Headings
- Polymorphism, Single-Stranded Conformational
- Molecular Sequence Data
- Isoenzymes
- In Situ Hybridization, Fluorescence
- Humans
- Glutathione Peroxidase
- Genetics & Heredity
- DNA
- Chromosomes, Human, Pair 14
- Chromosome Mapping
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Chu, F. F., Rohan de Silva, H. A., Esworthy, R. S., Boteva, K. K., Walters, C. E., Roses, A., … Pettenati, M. J. (1996). Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization. Genomics, 32(2), 272–276. https://doi.org/10.1006/geno.1996.0115
Chu, F. F., H. A. Rohan de Silva, R. S. Esworthy, K. K. Boteva, C. E. Walters, A. Roses, P. N. Rao, and M. J. Pettenati. “Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization.” Genomics 32, no. 2 (March 1996): 272–76. https://doi.org/10.1006/geno.1996.0115.
Chu FF, Rohan de Silva HA, Esworthy RS, Boteva KK, Walters CE, Roses A, et al. Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization. Genomics. 1996 Mar;32(2):272–6.
Chu, F. F., et al. “Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization.” Genomics, vol. 32, no. 2, Mar. 1996, pp. 272–76. Epmc, doi:10.1006/geno.1996.0115.
Chu FF, Rohan de Silva HA, Esworthy RS, Boteva KK, Walters CE, Roses A, Rao PN, Pettenati MJ. Polymorphism and chromosomal localization of the GI-form of human glutathione peroxidase (GPX2) on 14q24.1 by in situ hybridization. Genomics. 1996 Mar;32(2):272–276.
Published In
Genomics
DOI
EISSN
1089-8646
ISSN
0888-7543
Publication Date
March 1996
Volume
32
Issue
2
Start / End Page
272 / 276
Related Subject Headings
- Polymorphism, Single-Stranded Conformational
- Molecular Sequence Data
- Isoenzymes
- In Situ Hybridization, Fluorescence
- Humans
- Glutathione Peroxidase
- Genetics & Heredity
- DNA
- Chromosomes, Human, Pair 14
- Chromosome Mapping