Strong single-fiber sensory inputs to olfactory cortex: implications for olfactory coding.

Journal Article (Journal Article)

Olfactory information is first encoded in a combinatorial fashion by olfactory bulb glomeruli, which individually represent distinct chemical features of odors. This information is then transmitted to piriform (olfactory) cortex, via axons of olfactory bulb mitral and tufted (M/T) cells, where it is presumed to form the odor percept. However, mechanisms governing the integration of sensory information in mammalian olfactory cortex are unclear. Here we show that single M/T cells can make powerful connections with cortical pyramidal cells, and coincident input from few M/T cells is sufficient to elicit spike output. These findings suggest that odor coding is broad and distributed in olfactory cortex.

Full Text

Duke Authors

Cited Authors

  • Franks, KM; Isaacson, JS

Published Date

  • February 2, 2006

Published In

Volume / Issue

  • 49 / 3

Start / End Page

  • 357 - 363

PubMed ID

  • 16446140

International Standard Serial Number (ISSN)

  • 0896-6273

Digital Object Identifier (DOI)

  • 10.1016/j.neuron.2005.12.026


  • eng

Conference Location

  • United States