Functional neuroimaging of social and nonsocial cognitive control in autism.

Published

Journal Article

This study investigated cognitive control of social and nonsocial information in autism using functional magnetic resonance imaging. Individuals with autism spectrum disorders (ASDs) and a neurotypical control group completed an oddball target detection task where target stimuli were either faces or nonsocial objects previously shown to be related to circumscribed interests in autism. The ASD group demonstrated relatively increased activation to social targets in right insular cortex and in left superior frontal gyrus and relatively decreased activation to nonsocial targets related to circumscribed interests in multiple frontostriatal brain regions. Findings suggest that frontostriatal recruitment during cognitive control in ASD is contingent on stimulus type, with increased activation for social stimuli and decreased activation for nonsocial stimuli related to circumscribed interests.

Full Text

Duke Authors

Cited Authors

  • Sabatino, A; Rittenberg, A; Sasson, NJ; Turner-Brown, L; Bodfish, JW; Dichter, GS

Published Date

  • December 2013

Published In

Volume / Issue

  • 43 / 12

Start / End Page

  • 2903 - 2913

PubMed ID

  • 23636715

Pubmed Central ID

  • 23636715

Electronic International Standard Serial Number (EISSN)

  • 1573-3432

International Standard Serial Number (ISSN)

  • 0162-3257

Digital Object Identifier (DOI)

  • 10.1007/s10803-013-1837-4

Language

  • eng