Chlamydial intracellular survival strategies.
Publication
, Journal Article
Bastidas, RJ; Elwell, CA; Engel, JN; Valdivia, RH
Published in: Cold Spring Harb Perspect Med
May 1, 2013
Chlamydia trachomatis is the most common sexually transmitted bacterial pathogen and the causative agent of blinding trachoma. Although Chlamydia is protected from humoral immune responses by residing within remodeled intracellular vacuoles, it still must contend with multilayered intracellular innate immune defenses deployed by its host while scavenging for nutrients. Here we provide an overview of Chlamydia biology and highlight recent findings detailing how this vacuole-bound pathogen manipulates host-cellular functions to invade host cells and maintain a replicative niche.
Duke Scholars
Published In
Cold Spring Harb Perspect Med
DOI
EISSN
2157-1422
Publication Date
May 1, 2013
Volume
3
Issue
5
Start / End Page
a010256
Location
United States
Related Subject Headings
- Membrane Transport Proteins
- Life Cycle Stages
- Immunity, Innate
- Humans
- Host-Pathogen Interactions
- Golgi Apparatus
- Epithelial Cells
- Cytokines
- Chlamydia trachomatis
- Chlamydia Infections
Citation
APA
Chicago
ICMJE
MLA
NLM
Bastidas, R. J., Elwell, C. A., Engel, J. N., & Valdivia, R. H. (2013). Chlamydial intracellular survival strategies. Cold Spring Harb Perspect Med, 3(5), a010256. https://doi.org/10.1101/cshperspect.a010256
Bastidas, Robert J., Cherilyn A. Elwell, Joanne N. Engel, and Raphael H. Valdivia. “Chlamydial intracellular survival strategies.” Cold Spring Harb Perspect Med 3, no. 5 (May 1, 2013): a010256. https://doi.org/10.1101/cshperspect.a010256.
Bastidas RJ, Elwell CA, Engel JN, Valdivia RH. Chlamydial intracellular survival strategies. Cold Spring Harb Perspect Med. 2013 May 1;3(5):a010256.
Bastidas, Robert J., et al. “Chlamydial intracellular survival strategies.” Cold Spring Harb Perspect Med, vol. 3, no. 5, May 2013, p. a010256. Pubmed, doi:10.1101/cshperspect.a010256.
Bastidas RJ, Elwell CA, Engel JN, Valdivia RH. Chlamydial intracellular survival strategies. Cold Spring Harb Perspect Med. 2013 May 1;3(5):a010256.
Published In
Cold Spring Harb Perspect Med
DOI
EISSN
2157-1422
Publication Date
May 1, 2013
Volume
3
Issue
5
Start / End Page
a010256
Location
United States
Related Subject Headings
- Membrane Transport Proteins
- Life Cycle Stages
- Immunity, Innate
- Humans
- Host-Pathogen Interactions
- Golgi Apparatus
- Epithelial Cells
- Cytokines
- Chlamydia trachomatis
- Chlamydia Infections