Dysphagia in the setting of left ventricular assist device hemolysis.
Journal Article (Journal Article)
A 69-year-old man with advanced heart failure treated with a continuous-flow left ventricular assist device presented for evaluation of dark urine and severe dysphagia. Because of evidence of ongoing intravascular hemolysis with device dysfunction, there was a clinical suspicion for pump thrombosis. He had progressive end-organ dysfunction and was therefore treated with tissue plasminogen activator with prompt resolution in hemolysis and dysphagia. Although symptoms of smooth muscle dystonia could represent worsening heart failure in the setting of device failure, the observation may also be related to intravascular hemolysis as described in the prototypic hemolytic disease, paroxysmal nocturnal hemoglobinuria.
Full Text
Duke Authors
- Felker, Gary Michael
- Hernandez, Adrian Felipe
- Mentz, Robert John
- Milano, Carmelo Alessio
- Patel, Chetan B.
- Rogers, Joseph G.
- Schroder, Jacob Niall
Cited Authors
- Mentz, RJ; Schlendorf, K; Hernandez, AF; Milano, CA; Felker, GM; Blue, LJ; Schroder, JN; Rogers, JG; Patel, CB
Published Date
- 2013
Published In
Volume / Issue
- 59 / 3
Start / End Page
- 322 - 323
PubMed ID
- 23644623
Pubmed Central ID
- PMC4158398
Electronic International Standard Serial Number (EISSN)
- 1538-943X
Digital Object Identifier (DOI)
- 10.1097/MAT.0b013e31828bbb00
Language
- eng
Conference Location
- United States