Skip to main content

Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis.

Publication ,  Journal Article
Allen, BC; Bashir, MR; Dale, BM; Heye, TJ; Gupta, RT; Merkle, EM
Published in: J Comput Assist Tomogr
2013

OBJECTIVE: This study aimed to determine whether visible bone marrow enhancement (BME) at pelvic magnetic resonance angiography (MRA) correlates with anemia. METHODS: This is an institutional review board-approved, Health Insurance Portability and Accountability Act-compliant retrospective study. Seventy-five female patients with a hemoglobin (Hb) test within 10 days of an MRA examination of the pelvis are included, mean age of 46 years (range, 18-81 years). The BME was graded using a 4-point scale. Fifteen subjects had sufficient imaging data for calculation of quantitative perfusion parameters. Receiver operating characteristic and analysis of covariance were performed for 2 levels of anemia. RESULTS: Enhancement was visually present in 44% (33/75) of cases; 66% (19/29) of anemic subjects (Hb < 12 g/dL), and 30% (14/46) of nonanemic subjects (P = 0.002). Enhancement had a sensitivity of 87.5% and a specificity of 92.5% for the diagnosis of severe anemia (Hb < 10 g/dL); 88% (7/8) of these subjects had moderate to marked enhancement. A high extraction coefficient (Kep) in the iliac crest was associated with anemia, with an area under the curve of the receiver operating characteristic of 0.85 for mild anemia and 0.92 for severe anemia. CONCLUSIONS: Visible BME during time-resolved MRA is common and may be related to anemia.

Duke Scholars

Altmetric Attention Stats
Dimensions Citation Stats

Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

2013

Volume

37

Issue

3

Start / End Page

458 / 462

Location

United States

Related Subject Headings

  • Retrospective Studies
  • ROC Curve
  • Pelvis
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Meglumine
  • Magnetic Resonance Angiography
  • Humans
  • Female
 

Citation

APA
Chicago
ICMJE
MLA
NLM
Allen, B. C., Bashir, M. R., Dale, B. M., Heye, T. J., Gupta, R. T., & Merkle, E. M. (2013). Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis. J Comput Assist Tomogr, 37(3), 458–462. https://doi.org/10.1097/RCT.0b013e318283d549
Allen, Brian C., Mustafa R. Bashir, Brian M. Dale, Tobias J. Heye, Rajan T. Gupta, and Elmar M. Merkle. “Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis.J Comput Assist Tomogr 37, no. 3 (2013): 458–62. https://doi.org/10.1097/RCT.0b013e318283d549.
Allen BC, Bashir MR, Dale BM, Heye TJ, Gupta RT, Merkle EM. Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis. J Comput Assist Tomogr. 2013;37(3):458–62.
Allen, Brian C., et al. “Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis.J Comput Assist Tomogr, vol. 37, no. 3, 2013, pp. 458–62. Pubmed, doi:10.1097/RCT.0b013e318283d549.
Allen BC, Bashir MR, Dale BM, Heye TJ, Gupta RT, Merkle EM. Bone marrow enhancement during time-resolved magnetic resonance angiography of the pelvis. J Comput Assist Tomogr. 2013;37(3):458–462.

Published In

J Comput Assist Tomogr

DOI

EISSN

1532-3145

Publication Date

2013

Volume

37

Issue

3

Start / End Page

458 / 462

Location

United States

Related Subject Headings

  • Retrospective Studies
  • ROC Curve
  • Pelvis
  • Organometallic Compounds
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Meglumine
  • Magnetic Resonance Angiography
  • Humans
  • Female