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Plasmonic nanoprobes for intracellular sensing and imaging.

Publication ,  Journal Article
Yuan, H; Register, JK; Wang, H-N; Fales, AM; Liu, Y; Vo-Dinh, T
Published in: Analytical and bioanalytical chemistry
July 2013

Recent advances in integrating nanotechnology and optical microscopy offer great potential in intracellular applications with improved molecular information and higher resolution. Continuous efforts in designing nanoparticles with strong and tunable plasmon resonance have led to new developments in biosensing and bioimaging, using surface-enhanced Raman scattering and two-photon photoluminescence. We provide an overview of the nanoprobe design updates, such as controlling the nanoparticle shape for optimal plasmon peak position; optical sensing and imaging strategies for intracellular nanoparticle detection; and addressing practical challenges in cellular applications of nanoprobes, including the use of targeting agents and control of nanoparticle aggregation.

Duke Scholars

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Published In

Analytical and bioanalytical chemistry

DOI

EISSN

1618-2650

ISSN

1618-2642

Publication Date

July 2013

Volume

405

Issue

19

Start / End Page

6165 / 6180

Related Subject Headings

  • Surface Plasmon Resonance
  • Nanotechnology
  • Molecular Probes
  • Metal Nanoparticles
  • Luminescent Measurements
  • Humans
  • Cells
  • Animals
  • Analytical Chemistry
  • 40 Engineering
 

Citation

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ICMJE
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Yuan, H., Register, J. K., Wang, H.-N., Fales, A. M., Liu, Y., & Vo-Dinh, T. (2013). Plasmonic nanoprobes for intracellular sensing and imaging. Analytical and Bioanalytical Chemistry, 405(19), 6165–6180. https://doi.org/10.1007/s00216-013-6975-1
Yuan, Hsiangkuo, Janna K. Register, Hsin-Neng Wang, Andrew M. Fales, Yang Liu, and Tuan Vo-Dinh. “Plasmonic nanoprobes for intracellular sensing and imaging.Analytical and Bioanalytical Chemistry 405, no. 19 (July 2013): 6165–80. https://doi.org/10.1007/s00216-013-6975-1.
Yuan H, Register JK, Wang H-N, Fales AM, Liu Y, Vo-Dinh T. Plasmonic nanoprobes for intracellular sensing and imaging. Analytical and bioanalytical chemistry. 2013 Jul;405(19):6165–80.
Yuan, Hsiangkuo, et al. “Plasmonic nanoprobes for intracellular sensing and imaging.Analytical and Bioanalytical Chemistry, vol. 405, no. 19, July 2013, pp. 6165–80. Epmc, doi:10.1007/s00216-013-6975-1.
Yuan H, Register JK, Wang H-N, Fales AM, Liu Y, Vo-Dinh T. Plasmonic nanoprobes for intracellular sensing and imaging. Analytical and bioanalytical chemistry. 2013 Jul;405(19):6165–6180.
Journal cover image

Published In

Analytical and bioanalytical chemistry

DOI

EISSN

1618-2650

ISSN

1618-2642

Publication Date

July 2013

Volume

405

Issue

19

Start / End Page

6165 / 6180

Related Subject Headings

  • Surface Plasmon Resonance
  • Nanotechnology
  • Molecular Probes
  • Metal Nanoparticles
  • Luminescent Measurements
  • Humans
  • Cells
  • Animals
  • Analytical Chemistry
  • 40 Engineering