Anaplastic lymphoma kinase (ALK1) immunohistochemistry in diagnostic dermatopathology; an update.


Journal Article (Review)

The use of anaplastic lymphoma kinase antibodies (ALK1) as a diagnostic aid has expanded since becoming a routinely available immunohistochemical stain. Because the skin may be the site of a wide variety of hematolymphoid and fibroblastic proliferations, dermatopathologists commonly use ALK1 as part of a broader staining panel in diagnosing soft tissue and cutaneous hematolymphoid neoplasms. Furthermore, new entities and differential diagnostic contexts are emerging, which broaden the utility of ALK1 immunohistochemistry. We review the expanding role of ALK1 immunohistochemistry in contemporary dermatopathology.

Full Text

Duke Authors

Cited Authors

  • Papalas, JA; Kulbacki, E; Wang, E

Published Date

  • June 2013

Published In

Volume / Issue

  • 35 / 4

Start / End Page

  • 403 - 408

PubMed ID

  • 23689691

Pubmed Central ID

  • 23689691

Electronic International Standard Serial Number (EISSN)

  • 1533-0311

Digital Object Identifier (DOI)

  • 10.1097/DAD.0b013e31823d2943


  • eng

Conference Location

  • United States