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Contrast-enhanced free-breathing 3D T1-weighted gradient-echo sequence for hepatobiliary MRI in patients with breath-holding difficulties.

Publication ,  Journal Article
Reiner, CS; Neville, AM; Nazeer, HK; Breault, S; Dale, BM; Merkle, EM; Bashir, MR
Published in: Eur Radiol
November 2013

OBJECTIVE: Evaluate the image quality and diagnostic performance of a free-breathing 3D-gradient-echo sequence with radial acquisition (rGRE) compared with a Cartesian breath-hold 3D-GRE (cGRE) sequence on hepatobiliary phase MRI in patients with breath-holding difficulties. METHODS: Twenty-eight consecutive patients (15 males; mean age 61 ± 11.9 years) were analysed in this retrospective IRB-approved study. Breath-holding difficulties during gadoxetate-disodium-enhanced liver MRI manifested as breathing artefacts during dynamic-phase imaging. MRI included axial and coronal cGRE and a radially sampled rGRE sequence during the hepatobiliary phase. Two radiologists independently evaluated cGRE and rGRE images for image quality, liver lesion detection and conspicuity, and bile duct conspicuity on a four-point scale. RESULTS: Liver edge sharpness was significantly higher on rGRE images (P < 0.001). Overall image quality was slightly but significantly higher for rGRE than for cGRE (P < 0.001 and P = 0.039). Bile duct conspicuity scores of rGRE and cGRE were not significantly different. Sensitivity for detection of the 26 liver lesions was similar for rGRE and cGRE (81-77 % and 73-77 %, P = 0.5 and 1.0). Lesion conspicuity scores were significantly higher for rGRE for one reader (P = 0.012). CONCLUSION: In patients with breath-holding difficulties, overall image quality and liver lesion conspicuity on hepatobiliary phase MRI can be improved using the rGRE sequence. KEY POINTS: • Patients with diminished breath-holding capacities present a major challenge in abdominal MRI. • A free-breathing sequence for hepatobiliary-phase MRI can improve image quality. • Further advances are needed to reduce acquisition time of the free-breathing gradient-echo sequence.

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Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

November 2013

Volume

23

Issue

11

Start / End Page

3087 / 3093

Location

Germany

Related Subject Headings

  • Retrospective Studies
  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Liver Diseases
  • Imaging, Three-Dimensional
  • Humans
  • Gadolinium DTPA
  • Female
 

Citation

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Chicago
ICMJE
MLA
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Reiner, C. S., Neville, A. M., Nazeer, H. K., Breault, S., Dale, B. M., Merkle, E. M., & Bashir, M. R. (2013). Contrast-enhanced free-breathing 3D T1-weighted gradient-echo sequence for hepatobiliary MRI in patients with breath-holding difficulties. Eur Radiol, 23(11), 3087–3093. https://doi.org/10.1007/s00330-013-2910-2
Reiner, C. S., A. M. Neville, H. K. Nazeer, S. Breault, B. M. Dale, E. M. Merkle, and M. R. Bashir. “Contrast-enhanced free-breathing 3D T1-weighted gradient-echo sequence for hepatobiliary MRI in patients with breath-holding difficulties.Eur Radiol 23, no. 11 (November 2013): 3087–93. https://doi.org/10.1007/s00330-013-2910-2.
Reiner CS, Neville AM, Nazeer HK, Breault S, Dale BM, Merkle EM, et al. Contrast-enhanced free-breathing 3D T1-weighted gradient-echo sequence for hepatobiliary MRI in patients with breath-holding difficulties. Eur Radiol. 2013 Nov;23(11):3087–93.
Reiner, C. S., et al. “Contrast-enhanced free-breathing 3D T1-weighted gradient-echo sequence for hepatobiliary MRI in patients with breath-holding difficulties.Eur Radiol, vol. 23, no. 11, Nov. 2013, pp. 3087–93. Pubmed, doi:10.1007/s00330-013-2910-2.
Reiner CS, Neville AM, Nazeer HK, Breault S, Dale BM, Merkle EM, Bashir MR. Contrast-enhanced free-breathing 3D T1-weighted gradient-echo sequence for hepatobiliary MRI in patients with breath-holding difficulties. Eur Radiol. 2013 Nov;23(11):3087–3093.
Journal cover image

Published In

Eur Radiol

DOI

EISSN

1432-1084

Publication Date

November 2013

Volume

23

Issue

11

Start / End Page

3087 / 3093

Location

Germany

Related Subject Headings

  • Retrospective Studies
  • Reproducibility of Results
  • Nuclear Medicine & Medical Imaging
  • Middle Aged
  • Male
  • Liver Diseases
  • Imaging, Three-Dimensional
  • Humans
  • Gadolinium DTPA
  • Female