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Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.

Publication ,  Journal Article
Janssens, ACJW; Ioannidis, JPA; Bedrosian, S; Boffetta, P; Dolan, SM; Dowling, N; Fortier, I; Freedman, AN; Grimshaw, JM; Gulcher, J; Gwinn, M ...
Published in: Eur J Clin Invest
September 2011

• The rapid and continuing progress in gene discovery for complex diseases is fuelling interest in the potential application of genetic risk models for clinical and public health practice. • The number of studies assessing the predictive ability is steadily increasing, but they vary widely in completeness of reporting and apparent quality. • Transparent reporting of the strengths and weaknesses of these studies is important to facilitate the accumulation of evidence on genetic risk prediction. • A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS), building on the principles established by prior reporting guidelines. • These recommendations aim to enhance the transparency, quality and completeness of study reporting and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct or analysis.

Duke Scholars

Published In

Eur J Clin Invest

DOI

EISSN

1365-2362

Publication Date

September 2011

Volume

41

Issue

9

Start / End Page

1010 / 1035

Location

England

Related Subject Headings

  • Risk Assessment
  • Publishing
  • Models, Genetic
  • Humans
  • Guidelines as Topic
  • Genomics
  • Genome-Wide Association Study
  • Genome, Human
  • Genetic Testing
  • Genetic Research
 

Citation

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MLA
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Janssens, A. C. J. W., Ioannidis, J. P. A., Bedrosian, S., Boffetta, P., Dolan, S. M., Dowling, N., … Khoury, M. J. (2011). Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Clin Invest, 41(9), 1010–1035. https://doi.org/10.1111/j.1365-2362.2011.02493.x
Janssens, A Cecile J. W., John P. A. Ioannidis, Sara Bedrosian, Paolo Boffetta, Siobhan M. Dolan, Nicole Dowling, Isabel Fortier, et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.Eur J Clin Invest 41, no. 9 (September 2011): 1010–35. https://doi.org/10.1111/j.1365-2362.2011.02493.x.
Janssens ACJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, et al. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Clin Invest. 2011 Sep;41(9):1010–35.
Janssens, A. Cecile J. W., et al. “Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration.Eur J Clin Invest, vol. 41, no. 9, Sept. 2011, pp. 1010–35. Pubmed, doi:10.1111/j.1365-2362.2011.02493.x.
Janssens ACJW, Ioannidis JPA, Bedrosian S, Boffetta P, Dolan SM, Dowling N, Fortier I, Freedman AN, Grimshaw JM, Gulcher J, Gwinn M, Hlatky MA, Janes H, Kraft P, Melillo S, O’Donnell CJ, Pencina MJ, Ransohoff D, Schully SD, Seminara D, Winn DM, Wright CF, van Duijn CM, Little J, Khoury MJ. Strengthening the reporting of genetic risk prediction studies (GRIPS): explanation and elaboration. Eur J Clin Invest. 2011 Sep;41(9):1010–1035.
Journal cover image

Published In

Eur J Clin Invest

DOI

EISSN

1365-2362

Publication Date

September 2011

Volume

41

Issue

9

Start / End Page

1010 / 1035

Location

England

Related Subject Headings

  • Risk Assessment
  • Publishing
  • Models, Genetic
  • Humans
  • Guidelines as Topic
  • Genomics
  • Genome-Wide Association Study
  • Genome, Human
  • Genetic Testing
  • Genetic Research